/* Xin (Crystal) Qing: one visual system, styled like a calm scientific figure.
   Neutrals carry the page; the three area colors (plus the featured gold) are the only accents. */

:root {
  --wet: #2f9e6b;
  --omics: #3b72c4;
  --ml: #8a4fb3;
  --featured: #f2b84b;

  --paper: #fbfaf6;
  --paper-2: #f3f1ea;
  --ink: #1e2126;
  --ink-2: #4a4f57;
  --ink-3: #7a7f87;
  --rule: #dcd8cd;
  --dot-fill: #ffffff;

  --serif: "Iowan Old Style", "Charter", "Bitstream Charter", "Palatino Linotype", Palatino, Georgia, serif;
  --sans: system-ui, -apple-system, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;
  --mono: ui-monospace, "SF Mono", Menlo, Consolas, monospace;

  --measure: 1000px;
  --gutter: 16px;
  --gap: clamp(3rem, 7vw, 5.5rem);
  color-scheme: light dark;
}

@media (prefers-color-scheme: dark) {
  :root {
    --paper: #15171b;
    --paper-2: #1d2025;
    --ink: #e8e6e0;
    --ink-2: #b9b7b0;
    --ink-3: #8b8a85;
    --rule: #34373d;
    --dot-fill: #15171b;
  }
}

*,
*::before,
*::after { box-sizing: border-box; }

html { -webkit-text-size-adjust: 100%; }

body {
  margin: 0 auto;
  max-width: calc(var(--measure) + 2 * var(--gutter));
  padding: 0 var(--gutter);
  background: var(--paper);
  color: var(--ink);
  font: 400 1rem/1.6 var(--sans);
  overflow-wrap: anywhere;
}

a {
  color: inherit;
  text-decoration: underline;
  text-decoration-color: var(--rule);
  text-decoration-thickness: 1px;
  text-underline-offset: 0.18em;
  transition: text-decoration-color 0.15s ease;
}
a:hover { text-decoration-color: currentColor; }
:focus-visible {
  outline: 2px solid var(--ink);
  outline-offset: 3px;
  border-radius: 2px;
}

h1, h2, h3 { font-family: var(--serif); font-weight: 600; line-height: 1.25; }
h3 { font-size: 1.15rem; margin: 1.6rem 0 0.4rem; }
ul, ol { padding-left: 1.25rem; }
li { margin: 0.35rem 0; }
strong { font-weight: 650; }

/* ---------- Header ---------- */

.site-header {
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  justify-content: space-between;
  gap: 0.5rem 1.5rem;
  padding: 1.75rem 0 1.25rem;
  border-bottom: 1px solid var(--rule);
}
.site-header .name {
  font-family: var(--serif);
  font-size: 1.35rem;
  font-weight: 600;
  letter-spacing: -0.005em;
  text-decoration: none;
}
.site-header nav {
  display: flex;
  flex-wrap: wrap;
  gap: 0.25rem 1.1rem;
  font-size: 0.875rem;
  letter-spacing: 0.02em;
}
.site-header nav a {
  color: var(--ink-2);
  text-decoration: none;
  padding: 0.15rem 0;
}
.site-header nav a:hover { color: var(--ink); text-decoration: underline; }

/* ---------- Intro ---------- */

.intro {
  font-family: var(--serif);
  font-size: clamp(1.2rem, 2.6vw, 1.55rem);
  line-height: 1.45;
  color: var(--ink);
  max-width: 34em;
  margin: clamp(2rem, 6vw, 3.5rem) 0 1.5rem;
}

/* ---------- Sections: headed like figure panels (A, B, C...) ---------- */

main { counter-reset: panel; }
main > section { margin-top: var(--gap); }
main > section#map { margin-top: 0; }

section > h2 {
  counter-increment: panel;
  display: flex;
  align-items: baseline;
  gap: 0.75rem;
  font-family: var(--sans);
  font-size: 0.8rem;
  font-weight: 600;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--ink-2);
  margin: 0 0 1.25rem;
  padding-bottom: 0.6rem;
  border-bottom: 1px solid var(--rule);
}
section > h2::before {
  content: counter(panel, upper-alpha);
  font-family: var(--serif);
  font-size: 1.15rem;
  letter-spacing: 0;
  text-transform: none;
  color: var(--ink);
}

/* ---------- Map ---------- */

#map {
  display: grid;
  grid-template-columns: minmax(0, 1fr);
  gap: 1.25rem;
  align-items: center;
}
@media (min-width: 720px) {
  #map { grid-template-columns: minmax(0, 3fr) minmax(0, 2fr); gap: 2rem; }
}
#map svg {
  display: block;
  width: 100%;
  height: auto;
  overflow: visible;
}

.area {
  stroke-width: 1.25;
  transition: fill-opacity 0.2s ease, stroke-width 0.2s ease;
}
.area.is-lit { fill-opacity: 0.34; stroke-width: 2.25; }

.area-name {
  font-family: var(--sans);
  font-size: 13px;
  font-weight: 600;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  fill: var(--ink-2);
}
.area-name[data-area="wet"] { fill: var(--wet); }
.area-name[data-area="omics"] { fill: var(--omics); }
.area-name[data-area="ml"] { fill: var(--ml); }

.dot { cursor: pointer; text-decoration: none; }
.dot circle {
  fill: var(--dot-fill);
  stroke: var(--ink);
  stroke-width: 1.75;
  transform-box: fill-box;
  transform-origin: center;
  transition: transform 0.15s ease, stroke-width 0.15s ease;
}
.dot[data-region^="wet"] circle { fill: color-mix(in srgb, var(--wet) 45%, var(--dot-fill)); }
.dot[data-region^="omics"] circle { fill: color-mix(in srgb, var(--omics) 45%, var(--dot-fill)); }
.dot[data-region^="ml"] circle { fill: color-mix(in srgb, var(--ml) 45%, var(--dot-fill)); }
.dot[data-featured] circle { fill: var(--featured); stroke: var(--ink); }
.dot[data-soon] circle { stroke-dasharray: 3 2.5; }
.dot:hover circle,
.dot.is-active circle { transform: scale(1.3); stroke-width: 2.5; }
/* Keyboard focus: a thicker ring plus a soft halo (outlines on SVG links are unreliable). */
.dot:focus-visible { outline: none; }
.dot:focus-visible circle {
  transform: scale(1.35);
  stroke-width: 3;
  filter: drop-shadow(0 0 3px var(--ink));
}
/* Invisible hit area: never painted. Element-qualified so it beats the (0,2,1) dot circle rules. */
.dot circle.dot-hit,
.dot:hover circle.dot-hit,
.dot:focus circle.dot-hit,
.dot:focus-visible circle.dot-hit,
.dot.is-active circle.dot-hit { fill: transparent; stroke: none; }
.dot-label {
  font-family: var(--serif);
  font-size: 14px;
  font-weight: 600;
  fill: var(--ink);
  paint-order: stroke;
  stroke: var(--paper);
  stroke-width: 5px;
  stroke-linejoin: round;
}

/* SVG text scales with the map; keep labels legible when the map is phone-width. */
@media (max-width: 719.98px) {
  .area-name { font-size: 16px; letter-spacing: 0.06em; }
  .dot-label { font-size: 17px; }
}

#map-panel {
  min-height: 12rem;
  padding: 0.25rem 0 0.25rem 1.25rem;
  border-left: 1px solid var(--rule);
}
@media (max-width: 719.98px) {
  #map-panel { min-height: 0; padding: 1rem 0 0; border-left: 0; border-top: 1px solid var(--rule); }
}
#map-panel h3 { margin-top: 0; font-size: 1.2rem; }
#map-panel .summary { color: var(--ink-2); margin: 0 0 1rem; }

.thesis {
  font-size: 0.925rem;
  margin: 0.6rem 0;
  padding-left: 0.75rem;
  border-left: 3px solid var(--rule);
}
.thesis strong { font-weight: 600; }
.thesis.area-wet { border-left-color: var(--wet); }
.thesis.area-omics { border-left-color: var(--omics); }
.thesis.area-ml { border-left-color: var(--ml); }

/* ---------- Featured ---------- */

#featured > h3 {
  font-size: clamp(1.35rem, 3vw, 1.7rem);
  margin: 0 0 0.6rem;
  padding-left: 1rem;
  border-left: 4px solid var(--featured);
}
#featured > p { max-width: 42em; }
#featured > p:last-child { font-weight: 600; }
#featured > p:last-child a { text-decoration-color: var(--featured); text-decoration-thickness: 2px; }

.tools {
  font-family: var(--mono);
  font-size: 0.8rem;
  color: var(--ink-2);
}

/* ---------- Project cards ---------- */

.cards {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(min(100%, 220px), 1fr));
  gap: 1rem;
}
.card {
  position: relative;
  padding: 1rem 1rem 1rem 1.35rem;
  background: var(--paper-2);
  border-radius: 3px;
}
.card::before {
  content: "";
  position: absolute;
  inset: 0 auto 0 0;
  width: 4px;
  border-radius: 3px 0 0 3px;
  background: var(--stripe, var(--rule));
}
.card h3 { margin: 0 0 0.4rem; font-size: 1.05rem; }
.card h3 a { text-decoration: none; }
.card h3 a:hover { text-decoration: underline; }
.card p { margin: 0; font-size: 0.925rem; color: var(--ink-2); }
.card .meta {
  margin-top: 0.6rem;
  font-size: 0.75rem;
  letter-spacing: 0.06em;
  text-transform: uppercase;
  color: var(--ink-3);
}
.card.fun { background: transparent; border: 1px dashed var(--rule); }
.card.fun::before { width: 3px; }

/* ---------- Publications ---------- */

.pubs {
  list-style: none;
  padding: 0;
  counter-reset: pub;
}
.pubs li {
  counter-increment: pub;
  position: relative;
  padding-left: 2.25rem;
  margin: 0 0 1rem;
  font-size: 0.95rem;
}
.pubs li::before {
  content: counter(pub);
  position: absolute;
  left: 0;
  top: 0.1em;
  font-family: var(--serif);
  font-size: 0.9rem;
  color: var(--ink-3);
}
.pubs a { overflow-wrap: anywhere; }

.status {
  display: inline-block;
  margin-left: 0.35rem;
  padding: 0 0.45rem;
  font-size: 0.7rem;
  font-weight: 600;
  letter-spacing: 0.08em;
  text-transform: uppercase;
  line-height: 1.6;
  color: var(--ink-2);
  border: 1px solid var(--rule);
  border-radius: 999px;
  white-space: nowrap;
}

details { margin-top: 1.5rem; }
summary {
  cursor: pointer;
  font-size: 0.875rem;
  font-weight: 600;
  letter-spacing: 0.04em;
  color: var(--ink-2);
  width: fit-content;
}
summary:hover { color: var(--ink); }
details ul { font-size: 0.9rem; color: var(--ink-2); }

/* ---------- Service & About ---------- */

#service ul,
#about ul { list-style: none; padding: 0; }
#service li,
#about li {
  padding-left: 1rem;
  position: relative;
}
#service li::before,
#about li::before {
  content: "";
  position: absolute;
  left: 0;
  top: 0.7em;
  width: 5px;
  height: 5px;
  border-radius: 50%;
  border: 1px solid var(--ink-3);
}
#about > p:first-of-type { max-width: 42em; }
#about h3 {
  font-family: var(--sans);
  font-size: 0.8rem;
  letter-spacing: 0.12em;
  text-transform: uppercase;
  color: var(--ink-2);
}
.cookbook {
  margin-top: 1.5rem;
  font-size: 0.925rem;
  color: var(--ink-2);
}
.contact {
  margin-top: 1.75rem;
  font-family: var(--serif);
  font-size: 1.1rem;
}

/* ---------- Project pages ---------- */

.back {
  margin: 1.5rem 0 0;
  font-size: 0.875rem;
}
.back a { color: var(--ink-2); text-decoration: none; }
.back a:hover { color: var(--ink); text-decoration: underline; }

.project-head { margin: clamp(1.5rem, 5vw, 2.75rem) 0 0; }
.project-head h1 {
  font-size: clamp(1.6rem, 4.2vw, 2.4rem);
  letter-spacing: -0.01em;
  max-width: 22em;
  margin: 0.25rem 0 0.9rem;
}
.project-head.is-featured h1 {
  padding-left: 1rem;
  border-left: 4px solid var(--featured);
}
.eyebrow {
  margin: 0;
  font-size: 0.75rem;
  font-weight: 600;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--ink-3);
}
.tags {
  display: flex;
  flex-wrap: wrap;
  gap: 0.4rem;
  list-style: none;
  padding: 0;
  margin: 0 0 1.25rem;
}
.tag {
  margin: 0;
  padding: 0.1rem 0.6rem 0.1rem 0.5rem;
  font-size: 0.75rem;
  font-weight: 600;
  letter-spacing: 0.04em;
  color: var(--ink-2);
  border: 1px solid var(--rule);
  border-left: 4px solid var(--tag);
  border-radius: 3px;
}
.lede {
  font-family: var(--serif);
  font-size: clamp(1.1rem, 2.4vw, 1.3rem);
  line-height: 1.5;
  max-width: 36em;
  margin: 0 0 0.75rem;
}
.project-head .meta { margin: 0; font-size: 0.85rem; color: var(--ink-3); }

#problem > p,
#approach > p,
#results ul,
.team,
#cell-communication > p { max-width: 42em; }

.diagram {
  margin: 2rem 0;
  padding: clamp(1rem, 3vw, 1.75rem);
  background: var(--paper-2);
  border-radius: 4px;
}
@media (max-width: 559.98px) {
  /* Bleed to the screen edge so diagram labels stay as large as possible on phones. */
  .diagram { margin-inline: calc(-1 * var(--gutter)); padding: 1rem 6px; border-radius: 0; }
  .diagram figcaption { padding: 0 calc(var(--gutter) - 6px); }
}
.diagram svg {
  display: block;
  width: 100%;
  max-width: 560px;
  height: auto;
  margin: 0 auto;
  color: var(--ink);
}
.diagram svg text { font-family: var(--sans); }
.diagram figcaption {
  max-width: 42em;
  margin: 1rem auto 0;
  font-size: 0.85rem;
  color: var(--ink-2);
}

#results li::marker { color: var(--ink-3); }

.role {
  padding: 0.75rem 1.25rem 0.75rem 1.1rem;
  background: var(--paper-2);
  border-left: 4px solid var(--ink);
  border-radius: 0 4px 4px 0;
  max-width: 46em;
}
.role ul { margin: 0; }
.team {
  margin-top: 0.9rem;
  font-size: 0.9rem;
  color: var(--ink-2);
}

.links { list-style: none; padding: 0; }
.links li { margin: 0.5rem 0; }
.links a::after { content: " →"; }

/* ---------- Footer ---------- */

footer {
  margin-top: var(--gap);
  padding: 1.25rem 0 2rem;
  border-top: 1px solid var(--rule);
  font-size: 0.8rem;
  color: var(--ink-3);
}

@media (prefers-reduced-motion: reduce) {
  *,
  *::before,
  *::after {
    transition: none !important;
    animation: none !important;
    scroll-behavior: auto !important;
  }
}